Dr. Ishtiaq Hussain

Working as Assistant Professor in Department of Pharmacy, Abbottabad University of Science and Technology Havelian, Abbottabad, Pakistan since 2010. I got my doctor of Pharmacy (Pharm-D) degree in 2008 from University of Malakand Dir (L) kpk Pakistan with distinction (Gold Medal). I got my PhD degree from Jacobs University Bremen Germany in synthetic chemistry (Drug synthesis) in 2016 under the faculty development scholarship of HEC Islamabad.

• Organic Synthesis, Reaction Designing and Optimization, Asymmetric Synthesis, Multi-step drug synthesis, developing synthetic methodologies
• Natural product Chemistry
• Extraction, purification and characterization, Compounds structure elucidation through the use of modern analytical techniques i.e NMR, FT-IR, UV-Visible, GC, MS and HPLC etc,
• Biological and Pharmacological evaluation of natural products and synthetic compounds

1. Thomas C. Nugent, Hussein Ali El Damrany Hussein, Shahzad Ahmed, Foad Tehrani Najafian, Ishtiaq Hussain, Tony Georgiev,Mahmoud Khalaf Aljoumhawy” Carboxylate Salt Bridge‐Mediated Enamine Catalysis: Expanded Michael Reaction Substrate Scope and Facile Access to Antidepressant (R)‐Pristiq” Adv. Synth. Catal. 2017, 359, 2824 – 2831. Impact Factor: 5.85
2. Thomas C. Nugent, Peter Spiteller, Ishtiaq Hussain, Foad Tehrani Najafian, and Hussein Ali El Damrany Hussein“A Catalyst Directed Remote Epimer Switch during the Site-Selective Aldol Desymmetrization of Diketones, Adv. Synth. Catal. 2016, 358, 3706 – 3713. Impact Factor: 5.85
3. Thomas C. Nugent, Foad Tehrani Najafian, Hussein Ali El Damrany Hussein, and Ishtiaq Hussain “Beyond Chemoselectivity: Catalytic Site-Selective Aldolization of Diketones and Exploitation for Enantioselective Alzheimer Drug Candidate Synthesis, Chem. Eur, J, 2016, 22, 14342-14348. Impact Factor: 5.32
4. Inamullah H. Said, Ahmed Resk, Ishtiaq Hussain, Anne Grimbs, Abhinandan shrestha, Hartwig Schepker, Klaudia Brix, Matthias Ullrich, Nikolai Kuhnert “Metabolome comparison of bioactive and inactive Rhododendron extracts and Identification of an antibacterial cannabinoid(s) from Rhododendron collettianum” Phytochemical Analysis, 2017, 28,

5, 454-464. Impact Factor: 2.77 5. Ishtiaq Hussain, Akbar Ali “Exploring the Pharmacological Activities of Hydrazone Derivatives: A Review” J Phytochemistry Biochem. 2017, 1, 1-5.

6. Fawad Ali Shah, Lina Al Kury, Tao Li, Alam Zeb, Phil Ok Koh, Fang Liu, Zhen Tan, Ishtiaq Hussain, Arif ullah Khan, Yuhua Jiang, Shupeng Li, “Polydatin Attenuates Neuronal Loss via Reducing Neuroinflammation and Oxidative Stress in Rat MCAO Models” Frontier in pharmacology, 2019, Available online ( https://doi.org/10.3389/fphar.2019.00663). I.F: 4.22
7. Muhammad Zubair, Muhammad Sirajuddin, Ali Haider, Ishtiaq Hussain, Muhammad Nawaz Tahir, Saqib Ali “Organotin(IV) Complexes as Catalyst for Biodiesel Formation: Synthesis, Structural Elucidation and Computational Studies” Applied Organometallic Chemistry, 2019, Available online (https://doi.org/10.1002/aoc.5305) . Impact Factor: 3.14.
8. Saba Naz; Muhammad Sirajuddin, ; Ishtiaq Hussain; Akhtar Nadhman; Amna Gul; Sulaiman Faisal; Sana Ullah; Sammer Yousuf; Saqib ali, “2-Phenylbutyric Acid based Organotin(IV) Carboxylates; Synthesis, Spectroscopic Characterization, Antibacterial Action Against pant pathogens and In vitro hemolysis” Journal of Molecular Structure, 2019 (Available online (https://doi.org/10.1016/j.molstruc.2019.127378). Impact Factor: 2.46
9. Muhammad Zubair, Kaleem Ullah, Ali Haider, Muhammad Sirajuddin, Ishtiaq Hussain, Saqib Ali, Fouzia Perveen, Muhammad Nawaz Tahir “Synthesis, Structural Peculiarities, DFT and Molecular Docking Studies as well as Biological Potential of Newly Designed Two Azomethines” Journal of Molecular Structure (https://doi.org/10.1016/j.molstruc.2019.127574). Impact Factor: 2.46
10. Muhammad Khalid ,Akbar Ali, Jahrukh Tariq, Muhammad Nawaz Tahir, Hossein Asghar Rahnamaye Aliabad, Ishtiaq Hussain, Muhammad Ashfaq, Muhammad Usman Khan “Stabilization of Supramolecular Assembly of N-Substituted Benzylidene Acetohydrazide Analogs by Non-Covalent Interactions: A Concise Experimental and Theoretical Approach” ChemistrySelect 2020, 5, 10618– 10. Impact Factor: 1.81
11. Awais Ali, Fawad Ali Shah, Alam Zeb, Imran Malik, Arooj Mohsin Alvi, Lina Tariq Al Kury, Sajid Rashid, Ishtiaq Hussain, Najeeb ullah, Arif ullah khan, Phil Ok Koh, , Shupeng Li, “NF-κB Inhibitors Attenuate MCAO Induced Neurodegeneration and Oxidative Stress-A Reprofiling Approach” Frontier in Mol. Neurosciences, (Available online: https://doi.org/10.3389/fnmol.2020.00033). Impact Factor: 4.07
12. Farhat Ullah, Muhammad Ayaz, Abdul Sadiq, Muhammad Shahid, Ishtiaq Hussain, Jahangir Khan,“ A Review on the Potential Role of Medicinal Plants and Their Phytochemicals Against Foodborne Pathogens” Applied Sciences (Available online: https://doi.org/10.3390/app10134597). Impact Factor: 2.47
13. Ali N, Shah SWS, Khan J, Rehman S, Imran M, Hussain I, Shehbaz N, Jamshed H, Khan S “Pharmacotherapy-Based Problems in the Management of Diabetes Mellitus! Needs Much More to be Done, J Young Pharm. 2010,2 (3), 311-314. Impact Factor: 0.63
14. Ali N, Rehman S, Imran M, Hussain I, Shehbaz N, Jamshed H, Hayat A, Khan S, Anwar M J “The In-Practice Prescribing Pattern for Antibiotics in the Management of Diabetic Foot! Needs Much More to be Done” J Young Pharm. 2009,1 (4), 375-378. Impact Factor: 0.63
15. Najm Us Saqib , Rohana Adnan , Irfan Shah, Ishtiaq Hussain, “Sequential uptake of cadmium and methylene blue from binary solution using zeolite‐TiO2 modified porous CaCu3Ti4O12 photocatalyst” Environmental progress and sustainable energy, Jan 02, 2021, (Available online: https://doi.org/10.1002/ep.13595). Impact Factor: 1.98
16. Thomas C. Nugent, Falguni Goswami, Samarpita Debnath, Ishtiaq Hussain, Hussein Ali El Damrany Hussein, Alka Karn, Srinuvasu Nakka “Harnessing Additional Capability from in Water Reaction Conditions: Aldol versus Knoevenagel Chemoselectivity” Adv. Synth. Catal. Online May 19, 2021 (https://doi.org/10.1002/adsc.202100301) Impact Factor: 5.85
17. Thomas C. Nugent, Alice E. de Vos, Ishtiaq Hussain, Falguni Goswami, Samarpita Debnath, Hussein Ali El Damrany Hussein, “A Practitioner’s Guide to Chiral Amine Based Enantioselective Aldol Reactions: Common Substrates, Best Methods, and Defining Nuances” Asian journal of organic chemistry (Accepted manuscript) Impact Factor: 3.13

• Gold medalist of Pharmacy Department University of Malakand for the session 2003- 2007 •
• Got HEC Scholarship for PhD studies abroad (Germany) •
• Got German Government funding as postdoctoral research scientist for three months (May-July 2018) •
• Got a research grant of 2.67 million PKR “Efficient synthesis of novel hydrazones and oxadiazoles derivatives and evaluation of its pharmacological activities” from Higher Education Commission of Pakistan Islamabad under National Research Program for Universities (NRPU) program (2019