Antimicrobial susceptibility and frequency of methicillinresistant Staphylococcus aureus (MRSA) isolated from skin infected patients in District Peshawar, KPK, Pakistan

Antimicrobial susceptibility and frequency of methicillinresistant Staphylococcus aureus (MRSA) isolated from skin infected patients in District Peshawar, KPK, Pakistan

Abstract

Staphylococcus aureus (S. aureus) is an important pathogen which causes community associated Methicillin
resistant Staphylococcus aureus in fection (CA-MRSA) and hospital-associated Methicillin-resistant
Staphylococcus aureus (HA-MRSA). The objective of the current study was to investigate the frequency and
antimicrobial susceptibility of MRSA isolated from clinical settings of Peshawar. Clinical samples including pus
and swab were collected, followed by identification of MRSA by microscopic and biochemical based methods.
Out of 97 isolates, (27%) were found positive. The frequency of MRSA strains was more in females (57%) than in
males (43%). S. aureus was more prevalent in the age group 31-45 years with 42% followed by the age groups 46-
60, 16-30 and 1-15 years with 26%, 18%,and 14% respectively. S. aureus showed high resistance to Oxacillin
(27%), followed by Clarithromycin (18%), Amikacin and Doxycycline (16%), vancomycin (15%), Cefoxitin (13%),
Amoxicillin (12%), linezolid (8%) and Sulzone (7%). The present study highlighted that linezolid and Sulzone
were most effective to treat S. aureus infected patients.

 

No. of Pages
223-228
Volume
13
Author's Details
Iqbal Hussain1, Saba2, Muhammad Junaid, Rahim Dost Khan, Safia Hameed, Nasir Ali, Sifatullah
Research Field
Microbiology