Chaetomium endophytes: a repository of pharmacologically active metabolites

Chaetomium endophytes: a repository of pharmacologically active metabolites

Abstract

Abstract Fungal endophytes are group of fungi that grow
within the plant tissues without causing immediate signs of
disease and are abundant and diverse producers of bioactive
secondary metabolites. The Chaetomium genus of
kingdom fungi is considered to be a rich source of unique
bioactive metabolites. These metabolites belong to chemically
diverse classes, i.e., chaetoglobosins, xanthones,
anthraquinones, chromones, depsidones, terpenoids and
steroids. Cheatomium through production of diverse
metabolites can be considered as a potential source of
antitumor, cytotoxic, antimalarial, antibiotic and enzyme
inhibitory lead molecules for drug discovery. This review
covers isolation of Cheatomium endophytes, extraction and
isolation of metabolites and their biological activities.

No. of Pages
136
Volume
38
Author's Details
Nighat Fatima, Syed Aun Muhammad, Ibrar Khan, Muneer Ahmed Qazi, Irum Shahzadi, Amara Mumtaz, Muhammad Ali Hashmi, Abida Kalsoom Khan & Tariq Ismail
Research Field
Microbiology